Local infusion of low, but not high, doses of alcohol into the anterior ventral tegmental area causes release of accumbal dopamine

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Nicotinic acetylcholine receptors in the anterior, but not posterior, ventral tegmental area mediate ethanol-induced elevation of accumbal dopamine levels.

Ethanol-induced elevations of accumbal dopamine levels have been linked to the reinforcing properties of the drug. However, it has not yet been demonstrated where the primary point of action of ethanol is in the mesolimbic dopamine system, and there appear to be conflicting findings depending on methodology (electrophysiology, microdialysis, or intracranial self-administration). We have suggest...

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ژورنال

عنوان ژورنال: Open Journal of Psychiatry

سال: 2014

ISSN: 2161-7325,2161-7333

DOI: 10.4236/ojpsych.2014.41008